| Autor: |
Mariana Gospodinova, Francesc Formiga, Miguel-Ángel Idoate-Gastearena, Jose Nicolau, Oksana Drapkina, Winston Bonetti Yoshida, Arintaya Phrommintikul, JIANN-SHING JENG, Thomas Frieden, Vladimir Shulman, Yook-Chin Chia, Christopher Chen, Shaiful bahari Ismail, DIMITRIOS PARISSIS, Vicente Climent, John Cooke, Tomás Segura, Enrique Rodilla, Andrey Komarov, Joseph Eickmeyer, Prof Prakash P Punjabi, Yury Grinshtein, Martin James, Muriel Sprynger, Raymond Seet, Dragos Catalin Jianu, Ricardo Mourilhe-Rocha, Chaicharn Deerochanawong, Ru San Tan, Zhanna D. Kobalava, ALVARO AVEZUM, Monica Acevedo, Prof. Abdulhalim Kinsara, Iana Orlova, Maria Teresa Zanella, ELENA BOBESCU, Vijay Sharma, Veronika Lopukhova, Catalin Adrian Buzea, Yuri Karpov, Philippe Gabriel STEG, Stephen Hillis, Ali Azman Raymond, Jonathan Maltz, Albert Galyavich, Yomar Gonzalez, Hamidon Basri, Jeong-Taek Woo, Sung-Chun Tang, Ivo Petrov, Chirk Jenn Ng, TZUNG-DAU WANG, Sergei Shalaev, Marine Tanashyan, Gyorgy Gergely, Michael Lim, Mary Joan Macleod, Raffaella Pisapia, Jean Ferrieres, Alexander Nikonenko, Viktor Tashchuk, Jean-Luc Reny, Lea Maciel, Oleg Rodnenkov, Rodica Balasa, Farzanna Haffizulla, Mikhail Statsenko, Liviu Macovei, Albert Vernon Smith, Snezhanka Tisheva, Maria Glezer, Ji Hoe Heo, Umayya Musharrafieh, Emilian Bogdan Ignat, Teguh Santoso, John Malcolm Walker, Iurii Rudyk, Kyong Soo Park, Arman Postadzhiyan, Antonio Arauz, Veeda michelle Anlacan |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP |
| Popis: |
Background The extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated. Methods and Results Included were outpatients with established coronary artery disease who were enrolled in the REACH registry and were followed for 4 years. Angina at baseline was defined as necessitating episodic or permanent antianginal treatment. The primary end point was the composite of cardiovascular death, myocardial infarction, or stroke. Secondary end points included heart failure, cardiovascular hospitalizations, and coronary revascularization. The independent association between angina and first/total events was examined using Cox and logistic regression models. Out of 26 159 patients with established coronary artery disease, 13 619 (52%) had angina at baseline. Compared with patients without angina, patients with angina were more likely to be older, female, and had more heart failure and polyvascular disease ( P CI 1.11–1.27, P CI 0.99–1.14, P =0.11), and total primary end‐point events (adjusted risk ratio 1.08, CI 1.01–1.16, P =0.03). Patients with angina were at increased risk for heart failure (adjusted odds ratio 1.17, CI 1.06–1.28, P =0.002), cardiovascular hospitalizations (adjusted odds ratio 1.29, CI 1.21–1.38, P CI 1.13–1.34, P Conclusions Patients with stable coronary artery disease and angina have higher rates of future cardiovascular events compared with patients without angina. After adjustment, angina was only weakly associated with cardiovascular death, myocardial infarction, or stroke, but significantly associated with heart failure, cardiovascular hospitalization, and coronary revascularization. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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