Predicted concentrations of anticancer drugs in the aquatic environment: What should we monitor and where should we treat?
| Autor: | Kashyap Kumar Dubey, Patricia Luis, V.J. Pereira, Mrinal Kanti Mandal, Ankush Yadav, M.B. Cristóvão, B. Van der Bruggen, Shailesh Pandey, João G. Crespo, Raphael Janssens |
|---|---|
| Přispěvatelé: | UCL - SST/IMMC/IMAP - Materials and process engineering, Instituto de Biologia Experimental e Tecnológica - iBET, Central University of Haryana - Bioprocess Engineering Laboratory, National Institute of Technology Durgapur - n/a, KULeuven - n/a, Universidade Nova de Lisboa - LAQV-REQUIMTE, Universidade Nova de Lisboa - Instituto de Tecnologia Química e Biológica António Xavier |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Environmental Engineering
Hospitalized and outpatients Health Toxicology and Mutagenesis 0211 other engineering and technologies India Antineoplastic Agents Fresh Water 02 engineering and technology Wastewater 010501 environmental sciences Entry route 01 natural sciences Anticancer drugs Feces Consumption pattern Humans Environmental Chemistry Effective treatment Medicine Waste Management and Disposal 0105 earth and related environmental sciences 021110 strategic defence & security studies Portugal business.industry Predicted environmental concentrations Pollution Monitoring program Drug Utilization Hospitals Biotechnology Aquatic environment Housing business Water Pollutants Chemical Environmental Monitoring |
| Zdroj: | Journal of Hazardous Materials, Vol. 392, p. 122330 (2020) |
| Popis: | Anticancer drugs have been detected in the aquatic environment, they have a potent mechanism of action and their consumption is expected to drastically increase in the future. Consequently, it is crucial to routinely monitor the occurrence of anticancer drugs and to develop effective treatment options to avoid their release into the environment. Prior to implementing a monitoring program, it is important to define which anticancer drugs are more prone to be found in the surface waters. In this study the consumption of anticancer drugs in the Lisbon region (Portugal), Belgium and Haryana state (India) were used to estimate the concentrations that can be expected in surface waters. Moreover, one important aspect is to define the major entry route of anticancer drugs in the aquatic environment: is it hospital or household effluents? The results disclosed in this study showed that in Belgium and Lisbon, 94 % of the total amount of anticancer drugs were delivered to outpatients, indicating that household effluents are the primary input source of these drugs and thus, upgrading the treatment in the domestic wastewater facilities should be the focus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|