Vascular endothelial growth factor and subclinical atherosclerosis by carotid ultrasonography in Egyptian patients with Behçet’s disease
| Autor: | Mohammed M. El-Assal, Hanan H. Sabry, Howyda M. Kamal, Islam M. Elshazly, Sahar S Ganeb, Ayser Abd El-Hameed Fayed |
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| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
Pathology B-mode ultrasonography medicine.diagnostic_test business.industry Diastole Carotid ultrasonography Physical examination Behcet's disease Disease medicine.disease Gastroenterology Vascular endothelial growth factor chemistry.chemical_compound Behçet’s disease Rheumatology chemistry Intima-media thickness Internal medicine medicine Medical history Disease activity business |
| Zdroj: | The Egyptian Rheumatologist. (2):87-94 |
| ISSN: | 1110-1164 |
| DOI: | 10.1016/j.ejr.2012.12.001 |
| Popis: | Aim of the workThis study aimed to investigate serum levels of vascular endothelial growth factor (VEGF) and to measure common carotid intima media thickness (cc-IMT) in Egyptian patients with Behçet’s disease (BD) to evaluate their relations to disease activity and different clinical manifestations.Patients and methodsSeventy patients with BD and 70 healthy controls participated in this study. Behçet’s disease patients were subjected to detailed history taking, thorough clinical examination, disease activity assessment using the BD Current Activity Form (BDCAF) and laboratory investigation. Vascular endothelial growth factor levels were measured using ELISA. The carotid arteries were assessed for cc-IMT and plaques with a carotid high-resolution B-mode ultrasound.ResultsThe mean cc-IMT showed a significant difference in BD patients compared to controls (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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