Beyond Clinical High-Risk State for Psychosis: The Network Structure of Multidimensional Psychosis Liability in Adolescents
| Autor: | Eduardo Fonseca-Pedrero, Javier Ortuño-Sierra, Felix Inchausti, Juan Francisco Rodríguez-Testal, Martin Debbané |
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| Přispěvatelé: | Fundación BBVA, European Commission, Swiss National Science Foundation, Universidad de Sevilla. Departamento de Fisiología |
| Rok vydání: | 2020 |
| Předmět: |
lcsh:RC435-571
Schizotypy Population schizotypy clinical high risk Network Schizotypal 03 medical and health sciences 0302 clinical medicine lcsh:Psychiatry medicine education Complex dynamic system Original Research Psychiatry education.field_of_study complex dynamic system Anhedonia Mood Disorder Questionnaire Cognition Strengths and Difficulties Questionnaire Clinical high risk Mental health 3. Good health 030227 psychiatry Psychiatry and Mental health Prosocial behavior network schizotypal medicine.symptom Psychology 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Frontiers in Psychiatry idUS. Depósito de Investigación de la Universidad de Sevilla RIUR. Repositorio Institucional de la Universidad de La Rioja Frontiers in Psychiatry, Vol 10 (2020) |
| Popis: | [Objectives] The main goal of the present study was to analyze the network structure of schizotypy dimensions in a representative sample of adolescents from the general population. Moreover, the network structure between schizotypy, mental health difficulties, subjective well-being, bipolar-like experiences, suicide ideation and behavior, psychotic-like experiences, positive and negative affect, prosocial behavior, and IQ was analyzed. [Method] The study was conducted in a sample of 1,506 students selected by stratified random cluster sampling. The Oviedo Schizotypy Assessment Questionnaire, the Personal Wellbeing Index–School Children, the Paykel Suicide Scale, the Mood Disorder Questionnaire, the Strengths and Difficulties Questionnaire, the Prodromal Questionnaire–Brief, the Positive and Negative Affect Schedule for Children Shortened Version, and the Matrix Reasoning Test were used. [Results] The estimated schizotypy network was interconnected. The most central nodes in terms of standardized Expected Influence (EI) were ‘unusual perceptual experiences’ and ‘paranoid ideation’. Predictability ranged from 8.7% (‘physical anhedonia’) to 52.7% (‘unusual perceptual experiences’). The average predictability was 36.27%, implying that substantial variability remained unexplained. For the multidimensional psychosis liability network predictability values ranged from 9% (estimated IQ) to 74.90% (‘psychotic-like experiences’). The average predictability was 43.46%. The results of the stability and accuracy analysis indicated that all networks were accurately estimated. [Conclusions] The present paper points to the value of conceptualizing psychosis liability as a dynamic complex system of interacting cognitive, emotional, behavioral, and affective characteristics. In addition, provide new insights into the nature of the relationships between schizotypy, as index of psychosis liability, and the role played by risk and protective factors. EF-P was supported by la Convocatoria 2015 de “Ayudas Fundación BBVA a Investigadores y Creadores Culturales”, by “Ayudas Fundación BBVA a equipos de investigación científica 2017”, and FEDER La Rioja 2014-2020 (SRS 6FRSABC026). MD was supported by a grant from the Swiss National Science Foundation (100019_159440). |
| Databáze: | OpenAIRE |
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