Non-Hodgkin Lymphoma and Coexisting Primary Cancers
Autor: | Masahiko Kimura, Kouji Masuda, Hirokazu Matsuki, Junichi Omagari, Katsumasa Nakamura, Hiromi Terashima, Kenji Kawamoto, Naonobu Kunitake, Yoshiyuki Shioyama |
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Rok vydání: | 1999 |
Předmět: |
Male
Oncology Cancer Research medicine.medical_specialty medicine.medical_treatment Disease Adenocarcinoma Neoplasms Multiple Primary immune system diseases hemic and lymphatic diseases Internal medicine Humans Medicine neoplasms Aged Retrospective Studies Chemotherapy Clinical pathology business.industry Lymphoma Non-Hodgkin Stomach Cancer Middle Aged medicine.disease Lymphoma Surgery Radiation therapy medicine.anatomical_structure Female business |
Zdroj: | American Journal of Clinical Oncology. 22:283-285 |
ISSN: | 0277-3732 |
DOI: | 10.1097/00000421-199906000-00014 |
Popis: | The simultaneous occurrence of non-Hodgkin lymphoma (NHL) and primary cancers is rare, and the treatment strategy for both malignancies is unclear. The authors analyzed the clinical records of 10 patients with NHL and coexisting primary cancers. All patients initially had symptoms of NHL, and all carcinomas were found at the initial workup of NHL by chance. The most common primary sites of coexisting cancers were the stomach (six patients) and the colon (two). Histologically, the majority of NHLs were intermediate grade, and all lesions were B-cell type. All primary cancers were adenocarcinoma. Initially, NHL was treated with radiotherapy or chemotherapy. Six primary cancers were resected surgically or endoscopically after the remission of NHL. The remaining four patients received no treatment for primary cancers because of advanced stages or early relapse of NHL. Three patients died of NHL, one died of cancer, and six were still alive, five without evidence of disease and one with disease. The authors conclude that early detection of a coexisting cancer and appropriate treatment after the remission of NHL may increase the possibility of a cure. |
Databáze: | OpenAIRE |
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