Short-Term Changes in Skeletal Muscle Mass After Anthracycline Administration in Adolescent and Young Adult Sarcoma Patients
| Autor: | John A. Livingston, Savannah V. Wooten, Eugenie S. Kleinerman, Michael Roth, Behrang Amini, Susan C. Gilchrist, Joya Chandra, Michelle A.T. Hildebrandt |
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| Rok vydání: | 2022 |
| Předmět: |
Sarcopenia
Pediatrics medicine.medical_specialty Adolescent Anthracycline Soft Tissue Neoplasms Computed tomography Young Adult medicine Humans Anthracyclines Young adult Muscle Skeletal Retrospective Studies Muscle loss medicine.diagnostic_test business.industry Cancer Sarcoma medicine.disease Skeletal muscle mass humanities Oncology Pediatrics Perinatology and Child Health Brief Reports business |
| Zdroj: | J Adolesc Young Adult Oncol |
| ISSN: | 2156-535X 2156-5333 |
| DOI: | 10.1089/jayao.2021.0107 |
| Popis: | Identification of anthracycline-induced muscle loss is critical for maintaining health in adolescent and young adult (AYA) cancer patients. We used routine chest computed tomography (CT) scans to investigate changes in skeletal muscle of 16 AYA sarcoma patients at thoracic vertebrae 4 (T4) after anthracycline treatment. CT images were examined at three time points (prechemotherapy, postchemotherapy, and 1 year). Significant changes in total skeletal muscle index and density were seen after chemotherapy (p = 0.021 and p = 0.016, respectively) and at 1 year versus baseline (both p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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