Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination
| Autor: | Merike Vaher, Jekaterina Mazina-Šinkar, Mihkel Kaljurand, Jelena Gorbatsova, Piret Saar-Reismaa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Materials science
open source hardware business.industry capillary electrophoresis Pharmaceutical Science Organic chemistry Review Analytical Chemistry Enzymatic Assays monitoring Capillary electrophoresis QD241-441 Flow (mathematics) Chemistry (miscellaneous) Interfacing flow analysis Drug Discovery Molecular Medicine Physical and Theoretical Chemistry Process engineering business Monitoring tool |
| Zdroj: | Molecules, Vol 26, Iss 4918, p 4918 (2021) Molecules |
| ISSN: | 1420-3049 |
| Popis: | Flow analysis is the science of performing quantitative analytical chemistry in flowing streams. Because of its efficiency and speed of analysis, capillary electrophoresis (CE) is a prospective method for the monitoring of a flow composition withdrawn from various processes (e.g., occurring in bioreactors, fermentations, enzymatic assays, and microdialysis samples). However, interfacing CE to a various flow of interest requires further study. In this paper, several ingenious approaches on interfacing flow from various chemical or bioprocesses to a capillary electrophoresis instrument are reviewed. Most of these interfaces can be described as computer-controlled autosamplers. Even though most of the described interfaces waste too many samples, many interesting and important applications of the devices are reported. However, the lack of commercially available devices prevents the wide application of CE for flow analysis. On the contrary, this fact opens up a potential avenue for future research in the field of flow sampling by CE. |
| Databáze: | OpenAIRE |
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