Preoperative diagnosis of a giant cell tumor of soft tissue arising from the breast by ultrasound-guided core needle biopsy
| Autor: | Hiroko Bando, Emika Ichioka, Yukiko Tsushima, Yuzuru Kondo, Aya Sawa, Tatsuhiko Ikeda, Hisato Hara, Akiko Iguchi-Manaka |
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| Rok vydání: | 2018 |
| Předmět: |
Image-Guided Biopsy
Pathology medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Soft Tissue Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Biopsy Preoperative Care Medicine Humans Radiology Nuclear Medicine and imaging Giant Cell Tumors Breast Histiocyte Mastectomy Ultrasonography medicine.diagnostic_test business.industry Soft tissue Magnetic resonance imaging General Medicine Middle Aged Magnetic Resonance Imaging Giant cell Needles Immunohistochemistry 030211 gastroenterology & hepatology Female Biopsy Large-Core Needle business |
| Zdroj: | Journal of medical ultrasonics (2001). 46(2) |
| ISSN: | 1613-2254 |
| Popis: | Giant cell tumors of soft tissue (GCT-ST) arising in the breast are extremely rare. Herein, we report a case of a 45-year-old woman with a 5-cm mass in her left breast. Ultrasonography revealed a mainly well-circumscribed mass that contained a cystic lesion. Magnetic resonance imaging showed a fibrous capsule-covered mass that contained a high-intensity area, suggesting hemorrhaging. Ultrasound-guided core needle biopsy (CNB) revealed mononuclear histiocytic cells with a round shape or spindled appearance that was mixed with multinucleated giant cells. Immunohistochemical analysis revealed CD68-positive staining in the mononuclear and giant cells but negative staining for pancytokeratin. Preoperatively, the tumor was highly suspected of being GCT-ST. Histopathological results after a left mastectomy showed similar findings to CNB. The final diagnosis was GCT-ST in the breast. To the best of our knowledge, this is the first case report of a GCT-ST arising in the breast diagnosed by ultrasound-guided CNB. |
| Databáze: | OpenAIRE |
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