Catalytically-Promoted Analyte Derivatization Inside a Gas Chromatographic Inlet
| Autor: | William K. Fowler, Amber R. Wright, Kelly J. Gamble |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Analyte
Chromatography Gas Chromatography Chemistry Fluoroacetates Injection port General Medicine Mass spectrometry Heterogeneous catalysis Catalysis Article Analytical Chemistry chemistry.chemical_compound Inorganic Chemicals Reagent Acetamides Trifluoroacetic Acid Gas chromatography Organic Chemicals Derivatization |
| Zdroj: | Journal of Chromatographic Science. 48:466-472 |
| ISSN: | 1945-239X 0021-9665 |
| DOI: | 10.1093/chromsci/48.6.466 |
| Popis: | Reported here is a preliminary assessment of the feasibility of catalyzing on-line derivatization reactions inside the inlet (i.e., the injection port) of a gas chromatograph (GC) with solid heterogeneous catalysts. The experiments described here entail the installation of candidate catalysts inside the GC inlet liner and the subsequent injection of analyte/reagent mixtures onto the catalyst beds. Two catalysts are identified, each of which clearly catalyzes one of the chosen model derivatization reactions in the inlet of a GC. This result supports our hypothesis that on-line derivatizations can, in principle, be reproducibly catalyzed inside the GC inlet by solid heterogeneous catalysts and that the presence of such catalysts in the inlet do not necessarily cause a serious loss of instrument performance or chromatographic efficiency. |
| Databáze: | OpenAIRE |
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