Radioguidance for nonpalpable primary lesions and sentinel lymph node(s)
| Autor: | Rosemary Giuliano, Charles E. Cox, Douglas S. Reintgen, Emilia L. Dauway, Richard J. Gray |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Sentinel lymph node
Breast Neoplasms Metastatic carcinoma Iodine Radioisotopes Breast cancer medicine Humans Radionuclide Imaging Retrospective Studies Sentinel Lymph Node Biopsy business.industry General Medicine medicine.disease Primary tumor Lymphatic system Lymphatic Metastasis Technetium Tc 99m Sulfur Colloid Lymph Node Excision Female Surgery Lymph Nodes Lymph Breast carcinoma Nuclear medicine business Gamma probe |
| Zdroj: | The American Journal of Surgery. 182:404-406 |
| ISSN: | 0002-9610 |
| Popis: | Background: Radioguided surgery can also be used for the simultaneous guidance to a nonpalpable primary tumor and sentinel lymph nodes. Methods: Retrospective review of a prospective database. The surgeon used a gamma probe for guidance to an iodine-125 labeled titanium seed at the primary lesion and technetium-99 labeled sulfur colloid at the sentinel lymph node. Results: Forty-three patients with nonpalpable breast carcinoma underwent dual isotope radioguided surgery. The radioactive seed and primary lesion were retrieved in the first excision in all 44 patients (100%). Eleven patients (25%) had pathologically involved margins. Sentinel lymph node mapping was successful in 42 patients (98%). A mean of 2.4 sentinel nodes were excised and metastatic carcinoma was present in four patients (10%). Conclusions: Dual isotopes can be effectively used in breast cancer patients for simultaneous radioguidance to both a nonpalpable primary lesion and sentinel lymph node and allows for improved logistics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect