Prevalence and risk factors of intrahepatic cholestasis of pregnancy in a Chinese population

Autor:	Jin-Yan Li, Li Li, Xing-Xing Gao, Xue Lu, Yan Liu, Yuan-Hua Chen, Meng-Ying Ye, Guiying Nie, Wei Chen
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	medicine.medical_specialty Population lcsh:Medicine 03 medical and health sciences 0302 clinical medicine Medicine 030212 general & internal medicine education lcsh:Science Pregnancy education.field_of_study 030219 obstetrics & reproductive medicine Multidisciplinary business.industry Obstetrics Incidence (epidemiology) lcsh:R medicine.disease Cohort lcsh:Q Underweight medicine.symptom business Body mass index Cholestasis of pregnancy Cohort study
Zdroj:	Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
ISSN:	2045-2322
DOI:	10.1038/s41598-020-73378-5
Popis:	Studies on the risk factors for intrahepatic cholestasis of pregnancy (ICP) in a population-based cohort are lacking. We assess the prevalence and risk factors of ICP in a Chinese population. In this study, a cohort study was conducted that included 12,200 eligible pregnant women. The overall incidence of ICP in this cohort was 6.06%. With increasing maternal age, the incidence of ICP decreased in women younger than 30 years of age but increased in those older than 30. With increasing pre-pregnancy BMI, the incidence of ICP decreased if the pre-pregnancy BMI was less than 23 kg/m2 but increased if it was 23 kg/m2 or higher. Further analysis showed that the risk of ICP increased when maternal age was
Databáze:	OpenAIRE
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