Do pulmonary function tests improve risk stratification before cardiothoracic surgery?

Autor: Berhane Worku, Alexander Ivanov, Sorin J. Brener, Jordan Tailon, John F. Heitner, Jeremy A. Weingarten, Iosif Gulkarov, James Yossef, William M. Briggs, Terrence J. Sacchi, Anthony J. Tortolani
Rok vydání: 2015
Předmět:
Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
Vital capacity
Time Factors
Heart Diseases
030204 cardiovascular system & hematology
Risk Assessment
Severity of Illness Index
Pulmonary function testing
03 medical and health sciences
FEV1/FVC ratio
Pulmonary Disease
Chronic Obstructive

0302 clinical medicine
Predictive Value of Tests
Risk Factors
Internal medicine
Preoperative Care
medicine
Intubation
Intratracheal

Humans
Cardiac Surgical Procedures
Lung
Aged
COPD
Receiver operating characteristic
business.industry
Patient Selection
Length of Stay
Middle Aged
medicine.disease
Respiration
Artificial

Confidence interval
Cardiac surgery
Respiratory Function Tests
030228 respiratory system
ROC Curve
Cardiothoracic surgery
Elective Surgical Procedures
Area Under Curve
Cardiology
Surgery
Female
Cardiology and Cardiovascular Medicine
business
Respiratory Insufficiency
Zdroj: The Journal of thoracic and cardiovascular surgery. 151(4)
ISSN: 1097-685X
Popis: Objective To assess the added value of pulmonary function tests (PFTs) and different classifications of chronic obstructive pulmonary disease (COPD) to the Society of Thoracic Surgeons (STS) risk model using a clinical definition of lung disease for predicting outcomes after cardiothoracic (CT) surgery. Methods We evaluated consecutive patients who underwent nonemergency cardiac surgery and underwent PFTs before CT surgery. We used the STS risk model 2.73 to estimate the postoperative risk for respiratory failure (RF; defined as the need for mechanical ventilation for ≥72 hours, or reintubation), prolonged postoperative stay (PPLS; defined as >14 days), and 30-day all-cause mortality. We plotted the receiver operating characteristics curve for STS score for each adverse event, and compared the resulting area under the curve (AUC) with the AUC after adding PFT parameters and COPD classifications. Results Of the 1412 patients with a calculated STS score, 751 underwent PFTs. The AUC of the STS score was 0.65 (95% confidence interval [CI], 0.55-0.74) for RF, 0.67 (95% CI, 0.6-0.74) for prolonged postoperative length of stay (PPLS), and 0.74 (95% CI, 0.6-0.87) for death. None of the PFT parameters or COPD classifications added to the predictive ability of STS for RF, PPLS, or 30-day mortality. Conclusions Adding individual PFT parameters or different COPD classifications to STS score calculated using clinically based classification of lung disease did not improve model discrimination. Thus, routine preoperative PFTS may have limited clinical utility in patients undergoing CT surgery when the STS score is readily available.
Databáze: OpenAIRE