Fatal Metastatic Cutaneous Squamous Cell Carcinoma Evolving from a Localized Verrucous Epidermal Nevus
| Autor: | Amal Al Shaigy, Khalifa Al Naama, Hassan Riad, Hussein Al Sada, Khaled Mansour, Khairunnisa Hussain |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Keratoacanthoma
Nevus comedonicus medicine.medical_specialty Localized verrucous epidermal nevus integumentary system business.industry Epidermal nevus Dermatology lcsh:RL1-803 Cutaneous squamous cell carcinoma medicine.disease Fatal metastatic cutaneous squamous cell carcinoma Metastasis Malignant transformation lcsh:Dermatology Medicine Nevus Basal cell carcinoma Published online: October 2013 skin and connective tissue diseases business Porokeratosis Brain metastasis |
| Zdroj: | Case Reports in Dermatology Case Reports in Dermatology, Vol 5, Iss 3, Pp 272-282 (2013) |
| ISSN: | 1662-6567 |
| DOI: | 10.1159/000355605 |
| Popis: | A malignant transformation is known to occur in many nevi such as a sebaceous nevus or a basal cell nevus, but a verrucous epidermal nevus has only rarely been associated with neoplastic changes. Keratoacanthoma, multifocal papillary apocrine adenoma, multiple malignant eccrine poroma, basal cell carcinoma and cutaneous squamous cell carcinoma (CSCC) have all been reported to develop from a verrucous epidermal nevus. CSCC has also been reported to arise from other nevoid lesions like a nevus comedonicus, porokeratosis, a sebaceous nevus, an oral sponge nevus and an ichthyosiform nevus with CHILD syndrome. Here we report a case of progressive poorly differentiated CSCC arising from a localized verrucous epidermal nevus, which caused both spinal cord and brain metastasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|