| Autor: |
Ewa Janczewska, Marcin Kaczmarczyk, Beata Dobracka, Wiesław Kryczka, Jerzy Sieklucki, Iwona Orłowska, Agata Ruszala, Ewelina Tuchendler, Iwona Olszok, Waldemar Halota, Andrzej Horban, Joanna Wernik, Barbara Baka-Ćwierz, Marek Matukiewicz, Robert Flisiak, Krzysztof Tomasiewicz, K. Witczak-Malinowska, Rafał Krygier, Joanna Krzowska-Firych, Anna Strokowska, Robert Pleśniak, Bogumiła Korcz-Ondrzejek, Krzysztof Simon, Joanna Musialik, Anna Boroń-Kaczmarska, Maciej Jabłkowski, Błażej Rozpłochowski, Hanna Berak, Arkadiusz Pisula, Barbara Postawa-Kłosińska, Zbigniew Deroń, Dorota Zarębska-Michaluk, Jan Hałubiec, Aleksander Garlicki, Grzegorz Madej, Wojciech Chomczyk, Anna Piekarska, Barbara Sobala-Szczygieł, Jolanta Citko, Edyta Jezierska, Włodzimierz Mazur, Bronisława Szlauer, Katarzyna Sikorska, Anna Lachowicz-Wawrzyniak, Iwona Mozer-Lisewska, Witold Dobracki, Jacek Smykał, Krzysztof Nowak, Joanna Pogorzelska |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Clinical and Experimental Hepatology |
| Popis: |
The aim of the study Was to assess current prevalence of hepatitis C virus (HCV) genotypes in Poland, including their geographic distribution and changes in a given period of time. Material and methods Data were collected with questionnaires from 29 Polish centers and included data of patients diagnosed with HCV infection between 1 January 2013 and 31 March 2016. Results In total, data of 9800 patients were reported. The highest prevalence was estimated for genotype 1b (81.7%), followed by 3 (11.3%), 4 (3.5%), 1a (3.2%) and 2 (0.2%). Genotype 5 or 6 was reported in 6 patients only (0.1%). The highest prevalence of genotype 1 was observed in central (lodzkie, mazowieckie, świetokrzyskie), eastern (lubelskie) and southern (malopolskie, śląskie) Poland. The highest rate for genotype 3 was observed in south-western (dolnośląskie, lubuskie) and eastern (podlaskie, warminsko-mazurskie and podkarpackie) Poland. Compared to historical data, we observed an increasing tendency of G1 prevalence from 72.0% in 2003 to 87.5% in 2016, which was accompanied by a decrease of G3 (17.9% vs. 9.1%) and G4 (9.0% vs. 3.1%). Conclusions Almost 85% of patients with HCV in Poland are infected with genotype 1 (almost exclusively subgenotype 1b), and its prevalence shows an increasing tendency, accompanied by a decrease of genotypes 3 and 4. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
