Increased fragility fracture risk in Korean women who snore: a 10-year population-based prospective cohort study
Autor: | Wanhyung Lee, Soo Beom Choi, Deok Won Kim, Il Suk Lyu |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Time Factors lcsh:Diseases of the musculoskeletal system Osteoporosis 030209 endocrinology & metabolism Cohort Studies 03 medical and health sciences Fractures Bone 0302 clinical medicine Rheumatology Bone Density Risk Factors Surveys and Questionnaires Epidemiology Republic of Korea medicine Humans Orthopedics and Sports Medicine Prospective Studies Prospective cohort study Sleep disorder Sex Characteristics Frailty business.industry musculoskeletal neural and ocular physiology Hazard ratio Snoring Pre-screening Middle Aged medicine.disease Confidence interval nervous system diseases respiratory tract diseases Obstructive sleep apnea Fracture Population Surveillance Physical therapy Female lcsh:RC925-935 business Cohort study 030217 neurology & neurosurgery Follow-Up Studies Research Article |
Zdroj: | BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-7 (2017) BMC Musculoskeletal Disorders |
ISSN: | 1471-2474 |
Popis: | Background Snoring is frequently associated with obstructive sleep apnea (OSA). Previous studies have shown that bone mineral density was significantly lower in patients with OSA than in controls; however, these studies did not focus on fractures. Fragility fractures can lead to long-term disabilities and a decrease in quality of life. The present study aimed to investigate the association between snoring and fragility fractures. Methods This study included 2969 men and 3220 women aged 40 years and older from the Ansung and Ansan cohort studies in Korea. During a 10-year follow-up period, 129 and 273 fracture cases were reported in men and women, respectively. Results Severe snoring (6–7 nights per week or sleep disturbance by snoring in the next room) was a statistically significant risk factor for fracture (p = 0.006, hazard ratio 1.68, 95% confidence interval 1.16–2.43) after adjusting for covariates related to fragility fracture in women. However, both snoring and severe snoring groups did not show significant associations with the fracture risk in men. Conclusions Thus, information on the frequency of snoring in women may improve the accuracy of fragility fracture risk prediction, which can help in deciding whether intervention or treatment is necessary. Electronic supplementary material The online version of this article (doi:10.1186/s12891-017-1587-0) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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