Increased fragility fracture risk in Korean women who snore: a 10-year population-based prospective cohort study

Autor: Wanhyung Lee, Soo Beom Choi, Deok Won Kim, Il Suk Lyu
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Adult
Male
medicine.medical_specialty
Pediatrics
Time Factors
lcsh:Diseases of the musculoskeletal system
Osteoporosis
030209 endocrinology & metabolism
Cohort Studies
03 medical and health sciences
Fractures
Bone
0302 clinical medicine
Rheumatology
Bone Density
Risk Factors
Surveys and Questionnaires
Epidemiology
Republic of Korea
medicine
Humans
Orthopedics and Sports Medicine
Prospective Studies
Prospective cohort study
Sleep disorder
Sex Characteristics
Frailty
business.industry
musculoskeletal
neural
and ocular physiology
Hazard ratio
Snoring
Pre-screening
Middle Aged
medicine.disease
Confidence interval
nervous system diseases
respiratory tract diseases
Obstructive sleep apnea
Fracture
Population Surveillance
Physical therapy
Female
lcsh:RC925-935
business
Cohort study
030217 neurology & neurosurgery
Follow-Up Studies
Research Article
Zdroj: BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-7 (2017)
BMC Musculoskeletal Disorders
ISSN: 1471-2474
Popis: Background Snoring is frequently associated with obstructive sleep apnea (OSA). Previous studies have shown that bone mineral density was significantly lower in patients with OSA than in controls; however, these studies did not focus on fractures. Fragility fractures can lead to long-term disabilities and a decrease in quality of life. The present study aimed to investigate the association between snoring and fragility fractures. Methods This study included 2969 men and 3220 women aged 40 years and older from the Ansung and Ansan cohort studies in Korea. During a 10-year follow-up period, 129 and 273 fracture cases were reported in men and women, respectively. Results Severe snoring (6–7 nights per week or sleep disturbance by snoring in the next room) was a statistically significant risk factor for fracture (p = 0.006, hazard ratio 1.68, 95% confidence interval 1.16–2.43) after adjusting for covariates related to fragility fracture in women. However, both snoring and severe snoring groups did not show significant associations with the fracture risk in men. Conclusions Thus, information on the frequency of snoring in women may improve the accuracy of fragility fracture risk prediction, which can help in deciding whether intervention or treatment is necessary. Electronic supplementary material The online version of this article (doi:10.1186/s12891-017-1587-0) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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