Applications of nanotechnology in 3D printed tissue engineering scaffolds
| Autor: | Noah Z. Laird, Walla I. Malkawi, Satheesh Elangovan, Timothy M. Acri, Jaidev L. Chakka, Juliana C. Quarterman, Aliasger K. Salem |
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| Rok vydání: | 2021 |
| Předmět: |
Scaffold
Engineering 3d printed Pharmaceutical Science 3D printing Nanotechnology 02 engineering and technology 030226 pharmacology & pharmacy Article 03 medical and health sciences 0302 clinical medicine Tissue engineering Animals Humans Regeneration Tissue Engineering Tissue Scaffolds business.industry Regeneration (biology) General Medicine 021001 nanoscience & nanotechnology Applications of nanotechnology Printing Three-Dimensional 0210 nano-technology business Biotechnology |
| Zdroj: | Eur J Pharm Biopharm |
| ISSN: | 0939-6411 |
| DOI: | 10.1016/j.ejpb.2021.01.018 |
| Popis: | Tissue engineering is an interdisciplinary field that aims to combine life sciences and engineering to create therapies that regenerate functional tissue. Early work in tissue engineering mostly used materials as inert scaffolding structures, but research has shown that constructing scaffolds from biologically active materials can help with regeneration by enabling cell-scaffold interactions or release of factors that aid in regeneration. Three-dimensional (3D) printing is a promising technique for the fabrication of structurally intricate and compositionally complex tissue engineering scaffolds. Such scaffolds can be functionalized with techniques developed by nanotechnology research to further enhance their ability to stimulate regeneration and interact with cells. Nanotechnological components, nanoscale textures, and microscale/nanoscale printing can all be incorporated into the manufacture of 3D printed scaffolds. This review discusses recent advancements in the merging of nanotechnology with 3D printed tissue engineering scaffolds, with a focus on applications of nanoscale components, nanoscale texture, and innovative printing techniques and the effects observed in vitro and in vivo. |
| Databáze: | OpenAIRE |
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