Central Venous Catheter Salvage in Ambulatory Central Line-Associated Bloodstream Infections

Autor: Parsa Mirhaji, Suzette O. Oyeku, William J H Ford, Michael Drasher, Philip Zachariah, Elizabeth Klein, Moonseong Heo, Oghale Obaro-Best, Patricia DeLaMora, Rebecca E. Rosenberg, Barbara Rabin, David G. Bundy, Lisa Saiman, Michael L. Rinke, Alexandre Peshansky
Rok vydání: 2021
Předmět:
Zdroj: Pediatrics. 148(6)
ISSN: 1098-4275
Popis: BACKGROUND Guidelines for treatment of central line–associated bloodstream infection (CLABSI) recommend removing central venous catheters (CVCs) in many cases. Clinicians must balance these recommendations with the difficulty of obtaining alternate access and subjecting patients to additional procedures. In this study, we evaluated CVC salvage in pediatric patients with ambulatory CLABSI and associated risk factors for treatment failure. METHODS This study was a secondary analysis of 466 ambulatory CLABSIs in patients RESULTS A total of 460 ambulatory CLABSIs were included in our analysis. CVC salvage was attempted in 379 (82.3%) cases. Underlying diagnosis, CVC type, number of lumens, and absence of candidemia were associated with attempted salvage. Salvage was successful in 287 (75.7%) attempted cases. Underlying diagnosis, CVC type, number of lumens, and absence of candidemia were associated with successful salvage. In patients with malignancy, neutropenia within 30 days before CLABSI was significantly associated with both attempted salvage and successful salvage. CONCLUSIONS CVC salvage was often attempted and was frequently successful in ambulatory pediatric patients presenting with CLABSI.
Databáze: OpenAIRE