Tamoxifen-induced radiation recall dermatitis
| Autor: | Les B Rosen, Stratton B Grisoli, Erik J Soine, Alexandra Bourgeois |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Triamcinolone acetonide medicine.medical_treatment recall Dermatology Malignancy 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biopsy medicine skin and connective tissue diseases dermatitis tamoxifen medicine.diagnostic_test Recall business.industry General Medicine medicine.disease Surgery radiation Radiation therapy Radiation Recall Dermatitis 030220 oncology & carcinogenesis business Mastectomy Tamoxifen medicine.drug |
| Zdroj: | Bourgeois, Alexandra; Grisoli, Stratton B; Soine, Erik J; & Rosen, Les B. (2017). Tamoxifen-induced radiation recall dermatitis. Dermatology Online Journal, 23(2). Retrieved from: http://www.escholarship.org/uc/item/1d38c9c7 |
| ISSN: | 1087-2108 |
| DOI: | 10.5070/d3232033964 |
| Popis: | Author(s): Bourgeois, Alexandra; Grisoli, Stratton B; Soine, Erik J; Rosen, Les B | Abstract: Background: Radiation recall dermatitis (RRD) canpresent days to years after radiation exposure andis most commonly caused by chemotherapy drugs,with tamoxifen-induced radiation recall dermatitisbeing exceptionally rare. Purpose: To report a newcase of tamoxifen-induced radiation recall dermatitisafter 4.5 years of tamoxifen exposure, making this thelongest time of onset to RRD after tamoxifen initiation.Materials and Methods: The case of a woman withtamoxifen-induced RRD is presented. Using PubMedand Google Scholar, the terms tamoxifen, radiation,recall, dermatitis were searched. Relevant citationswere utilized and discussed. Results: An adult womanwith history of inflammatory breast carcinomadeveloped an erythematous, scaly, tender plaquelocalized to previously irradiated skin of the left chestafter more than four years of tamoxifen therapy. Thepatient was diagnosed with RRD and was treated withtopical triamcinolone 0.1% cream twice daily to theaffected areas. The patient experienced subsequentrapid improvement despite continuation of tamoxifentreatment. Biopsy revealed changes consistent withradiation dermatitis with no evidence of malignancy.Conclusion: Radiation recall dermatitis can havesignificant impact on affected patients and can posea diagnostic dilemma for clinicians who may mistakeRRD for infection or recurrence of malignancy. It isimportant to be familiar with the presenting signs andsymptoms of this entity so that affected patients canreceive timely and appropriate therapy. |
| Databáze: | OpenAIRE |
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