Transition from room temperature to cold‐stored platelets for the preservation of blood inventories during the COVID‐19 pandemic
| Autor: | Camille M. van Buskirk, Daryl J. Kor, James R. Stubbs, Matthew A. Warner, Emil B. Kurian, Scott A. Hammel |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Immunology Hemorrhage Platelet Transfusion 030204 cardiovascular system & hematology surgery 03 medical and health sciences 0302 clinical medicine Interquartile range COVID‐19 Pandemic medicine Immunology and Allergy Humans Platelet Original Research transfusion Aged business.industry SARS-CoV-2 Temperature COVID-19 Hematology Vascular surgery Middle Aged Cardiac surgery Transplantation Platelet transfusion Blood Preservation Anesthesia Hemostasis platelets hemostasis Female business 030215 immunology |
| Zdroj: | Transfusion |
| ISSN: | 1537-2995 0041-1132 |
| Popis: | Introduction The COVID-19 pandemic has placed great strain on blood resources. In an effort to extend platelet shelf-life and minimize waste, our institution transitioned room-temperature to cold-stored platelets for administration to bleeding patients. Study design and methods We describe the administrative and technical processes involved in transitioning room-temperature platelets to cold-storage in April 2020. Additionally, we describe the clinical utilization of cold-stored platelets in the first month of this practice change, with a focus on changes in platelet counts after transfusion, hemostasis, and safety outcomes. Results A total of 61 cold-stored platelet units were transfused to 40 bleeding patients, with a median (interquartile range) of 1 (1, 2) units per patient. The median age was 68 (59, 73) years; 58% male. Median pre-transfusion and post-transfusion platelets counts were 88 (67, 109) and 115 (93, 145). 95% of transfusions were administered in the operating room; 57% cardiac surgery, 20% vascular surgery, 8% general surgery, and 5% solid-organ transplantation. Hemostasis was deemed to be adequate in all cases after transfusion. There were no transfusion reactions. One patient (3%) experienced a fever and infection within 5 days of transfusion, which was unrelated to transfusion. Median hospital length of stay was 8.5 (6, 17) days. Two patients (5%) died in the hospital of complications not related to transfusion. Conclusion Cold-stored platelet utilization was associated with adequate hemostasis and no overt signal for patient harm. Conversion from room-temperature to cold-stored platelets may be one method of reducing waste in times of scarce blood inventories. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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