Celiac Disease: Fallacies and Facts

Autor: Ciaran P. Kelly, Jocelyn A. Silvester, Amelie Therrien
Rok vydání: 2021
Předmět:
Zdroj: Am J Gastroenterol
ISSN: 1572-0241
0002-9270
Popis: Our understanding of the pathophysiology of celiac disease has progressed greatly over the last 25 years, yet some fallacies about the clinical characteristics and management persist. Worldwide epidemiologic data are now available showing that celiac disease is ubiquitous. An elevated body mass index is common at the time of the diagnosis. The gluten-free diet is an imperfect treatment for celiac disease; not all individuals show a response. This diet is widely used by people without celiac disease, and symptomatic improvement on a gluten-free diet is not sufficient for diagnosis. Finally, the gluten-free diet is burdensome, difficult to achieve and thus has an incomplete efficacy, opening exciting opportunities for novel, non-dietary, treatments.
Databáze: OpenAIRE