Celiac Disease: Fallacies and Facts
Autor: | Ciaran P. Kelly, Jocelyn A. Silvester, Amelie Therrien |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
MEDLINE Disease Article Body Mass Index Diagnosis Differential Diet Gluten-Free 03 medical and health sciences 0302 clinical medicine medicine Humans Genetic Predisposition to Disease Intensive care medicine Evidence-Based Medicine Hepatology business.industry Gastroenterology nutritional and metabolic diseases digestive system diseases Celiac Disease 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Epidemiologic data Edible Grain business Elevated body mass index |
Zdroj: | Am J Gastroenterol |
ISSN: | 1572-0241 0002-9270 |
Popis: | Our understanding of the pathophysiology of celiac disease has progressed greatly over the last 25 years, yet some fallacies about the clinical characteristics and management persist. Worldwide epidemiologic data are now available showing that celiac disease is ubiquitous. An elevated body mass index is common at the time of the diagnosis. The gluten-free diet is an imperfect treatment for celiac disease; not all individuals show a response. This diet is widely used by people without celiac disease, and symptomatic improvement on a gluten-free diet is not sufficient for diagnosis. Finally, the gluten-free diet is burdensome, difficult to achieve and thus has an incomplete efficacy, opening exciting opportunities for novel, non-dietary, treatments. |
Databáze: | OpenAIRE |
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