Pavlovian Conditioning of Larval Drosophila: An Illustrated, Multilingual, Hands-On Manual for Odor-Taste Associative Learning in Maggots
| Autor: | Matthieu Louis, Teiichi Tanimura, Timo Saumweber, Rupert D. V. Glasgow, Yi-chun Chen, Jeanette Thum, Naoko Toshima, Roland Biernacki, Michael Schleyer, Reinhard F. Stocker, Manuela Marescotti, Fabio Benfenati, Birgit Michels, Claire Eschbach, Gonzalo Arias-Gil, Bertram Gerber |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
cognition Computer science Experimental psychology Cognitive Neuroscience Context (language use) computer.software_genre Science education taste memory 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Methods Psychology Set (psychology) Biomedicine Cognitive science reinforcement association cognition memory olfaction reinforcement taste business.industry Neurosciences association Associative learning 030104 developmental biology Neuropsychology and Physiological Psychology Expression (architecture) Connectome Cognitive Sciences Artificial intelligence business computer 030217 neurology & neurosurgery Natural language processing olfaction Neuroscience |
| Zdroj: | Frontiers in Behavioral Neuroscience Frontiers in behavioral neuroscience, 11: 45 |
| ISSN: | 1662-5153 |
| Popis: | Larval Drosophila offer a study case for behavioral neurogenetics that is simple enough to be experimentally tractable, yet complex enough to be worth the effort. We provide a detailed, hands-on manual for Pavlovian odor-reward learning in these animals. Given the versatility of Drosophila for genetic analyses, combined with the evolutionarily shared genetic heritage with humans, the paradigm has utility not only in behavioral neurogenetics and experimental psychology, but for translational biomedicine as well. Together with the upcoming total synaptic connectome of the Drosophila nervous system and the possibilities of single-cell-specific transgene expression, it offers enticing opportunities for research. Indeed, the paradigm has already been adopted by a number of labs and is robust enough to be used for teaching in classroom settings. This has given rise to a demand for a detailed, hands-on manual directed at newcomers and/or at laboratory novices, and this is what we here provide. The paradigm and the present manual have a unique set of features: (1) The paradigm is cheap, easy, and robust; (2) The manual is detailed enough for newcomers or laboratory novices; (3) It briefly covers the essential scientific context; (4) It includes sheets for scoring, data analysis, and display; (5) It is multilingual: in addition to an English version we provide German, French, Japanese, Spanish and Italian language versions as well. The present manual can thus foster science education at an earlier age and enable research by a broader community than has been the case to date. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|