Cell division and sister chromatid exchanges in 45,X/46,X,i(Xq) mosaicism

Autor:	Kyra Michalova, Málková J, Josef Urban
Rok vydání:	1977
Předmět:	Sex Chromosomes Time Factors X Chromosome Cell division Mosaicism Cell Cycle Chromatids Cell cycle Biology Molecular biology Peripheral blood Lectins Genetics Humans Sister chromatids Female Metabolic disease Sex Chromosome Aberrations Genetics (clinical)
Zdroj:	Human Genetics. 39:87-90
ISSN:	1432-1203 0340-6717
DOI:	10.1007/bf00273155
Popis:	The kinetics of cell division and sister chromatid exchanges were studied in PHA-stimulated short-term cultivations of peripheral blood by means of the BUDR/FPG technique in controls and in five patients with 45,X/46,X,i(Xq) mosaicism. No significant differences in the length of the cell cycle were observed between 45,X/46,X,i(Xq) and control 46,XX cells. The number of SCE on late i(Xq) was only nonsignificantly elevated (0.6 per i(Xq)) against the value expected on the basis of its relative length.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81849aa8881131e31d941b459268e02 https://doi.org/10.1007/bf00273155 Zobrazit plný text záznamu Full text from SpringerLink