Protein and Imaging Biomarkers in the Eye for Early Detection of Alzheimer's Disease
| Autor: | Manju L Subramanian, Steven Ness, Joshua S Agranat, Nicole Siegel, Shaunt Fereshetian, Thor D. Stein |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
retina
lens Early detection Disease Review Bioinformatics vitreous 03 medical and health sciences 0302 clinical medicine medicine Dementia crystalline business.industry General Neuroscience amyloid medicine.disease eye Psychiatry and Mental health Clinical Psychology cataract 030221 ophthalmology & optometry Retinal imaging Geriatrics and Gerontology business Alzheimer’s disease 030217 neurology & neurosurgery |
| Zdroj: | Journal of Alzheimer's Disease Reports |
| ISSN: | 2542-4823 |
| Popis: | Alzheimer’s disease (AD) is one of the most common causes of dementia worldwide. Although no formal curative therapy exists for the treatment of AD, considerable research has been performed to identify biomarkers for early detection of this disease, and thus improved subsequent management. Given that the eye can be examined and imaged non-invasively with relative ease, it has emerged as an exciting area of research for evidence of biomarkers and to aid in the early diagnosis of AD. This review explores the current understanding of both protein and retinal imaging biomarkers in the eye. Herein, primary findings in the literature regarding AD biomarkers associated with the lens, retina, and other ocular structures are reviewed. |
| Databáze: | OpenAIRE |
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