Formation of an aminoacyl-S-enzyme intermediate is a key step in the biosynthesis of chloramphenicol
Autor: | Jason K. Sello, Michael G. Thomas, Christopher T. Walsh, Michelle Pacholec |
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Rok vydání: | 2007 |
Předmět: |
chemistry.chemical_classification
Time Factors biology Stereochemistry Chloramphenicol Organic Chemistry food and beverages biology.organism_classification Biochemistry Streptomyces carbohydrates (lipids) chemistry.chemical_compound Kinetics Enzyme chemistry Biosynthesis parasitic diseases medicine NADH NADPH Oxidoreductases Physical and Theoretical Chemistry medicine.drug |
Zdroj: | Organicbiomolecular chemistry. 5(11) |
ISSN: | 1477-0520 |
Popis: | Herein we report the first biochemical characterization of an enzyme involved in the biosynthesis of chloramphenicol that provides new insights into the origins of the antibiotic. |
Databáze: | OpenAIRE |
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