Palladium-Catalyzed C—N Bond Formation: Synthesis of 1-Aryl-1H-pyrazoles from β-Bromovinyl Aldehydes and Arylhydrazines

Autor:	Daksha B. Patel, Chan Sik Cho
Rok vydání:	2006
Předmět:	Aryl Phosphorus Organic Chemistry chemistry.chemical_element General Medicine Bond formation Biochemistry Toluene Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Chelation Palladium catalyst Palladium
Zdroj:	ChemInform. 37
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200641108
Popis:	Cyclic and acyclic β-bromovinyl aldehydes are cyclized with an array of arylhydrazines in toluene at 125 °C in the presence of a palladium catalyst and a phosphorus chelating ligand together with NaOtBu to give 1-aryl-1H-pyrazoles in moderate to good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ffbaee19b8b7b9dc9b758776a0180f https://doi.org/10.1002/chin.200641108 Zobrazit plný text záznamu Plný text