Psoriasis during natalizumab treatment for multiple sclerosis
| Autor: | Jorge Millán-Pascual, Pablo del Saz-Saucedo, Ignacio Rueda-Medina, Laura Turpín-Fenoll, Santiago Navarro-Muñoz |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Neurology Multiple Sclerosis Side effect business.industry Multiple sclerosis Natalizumab Treatment outcome medicine.disease Antibodies Monoclonal Humanized Dermatology Treatment Outcome Psoriasis Monoclonal medicine Humans Female Neurology (clinical) business medicine.drug Neuroradiology |
| Zdroj: | Journal of neurology. 259(12) |
| ISSN: | 1432-1459 |
| Popis: | Beta-interferon therapy is known to trigger psoriasis, but this effect has not been previously reported for other multiple sclerosis treatments, such as natalizumab. The following is a case report. A 31-year-old woman affected by psoriasis and relapsing-remitting multiple sclerosis suffered a severe worsening of psoriasis symptoms during natalizumab treatment and acquired a drug-resistant course. This case suggests that aggravation of psoriasis might be a rare side effect of natalizumab, and that clinicians should be aware of the possibility of paradoxical activation of autoimmune diseases during its treatment. |
| Databáze: | OpenAIRE |
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