Can Pancreatitis Be Associated with Amiodarone Hepatotoxicity?
| Autor: | Suriya V. Sastri, John B. Marshall, Alberto A. Diaz-Arias |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Abdominal pain Pancreatic disease Nausea Amiodarone Gastroenterology Epigastric pain Internal medicine medicine Humans Aged business.industry Lipase medicine.disease Pancreatitis Amylases Toxicity Vomiting Chemical and Drug Induced Liver Injury medicine.symptom business medicine.drug |
| Zdroj: | Journal of Clinical Gastroenterology. 12:70-73 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/00004836-199002000-00018 |
| Popis: | We report a patient with classical features of amiodarone hepatotoxicity who died of progressive liver failure. Throughout the course of his illness, he had epigastric pain, nausea, vomiting, and persistent mild to moderate elevation of amylase and lipase in his serum and peritoneal fluid. Pancreatitis due to amiodarone has not been reported. We raise the question of whether or not the pancreas is yet another organ subject to amiodarone toxicity and speculate as to possible pathogenesis. We suggest that patients on amiodarone who develop abnormal liver enzymes, nausea, vomiting, or abdominal pain be evaluated not only for hepatotoxicity, but for pancreatitis as well. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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