Bone disease during chronic antiepileptic drug therapy: general versus specific risk factors
| Autor: | K. Beerhorst, Albert P. Aldenkamp, Pauline Verschuure, Sylvie J.M. van der Kruijs, In Y. Tan |
|---|---|
| Přispěvatelé: | Signal Processing Systems, Medical signal processing, Promovendi MHN, Klinische Neurowetenschappen, RS: MHeNs School for Mental Health and Neuroscience |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Databases Factual Bone disease Fracture risk medicine.medical_treatment Osteoporosis Antiepileptic drug Specific risk Rickets Epilepsy Bone Density Risk Factors Anticonvulsant Bone mineral density Humans Medicine Intensive care medicine business.industry Osteopenia medicine.disease Neurology Physical therapy Anticonvulsants Neurology (clinical) Bone Diseases business |
| Zdroj: | Journal of the Neurological Sciences, 331(1-2), 19-25. Elsevier Journal of the Neurological Sciences, 331(1-2), 19-25. Elsevier Science |
| ISSN: | 0022-510X |
| Popis: | An increasing number of studies suggest a direct effect of antiepileptic drug (AED) therapy on bone health: Patients on chronic AED therapy may have an increased risk of fractures, reduced bone mineral density, osteopenia, and osteoporosis. In an attempt to distinguish general and specific risk factors, this review examines the available empirical research. The pathophysiology is discussed and guidelines for early detection and treatment options are proposed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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