Campylobacter genotypes from food animals, environmental sources and clinical disease in Scotland 2005/6
| Autor: | Samuel K. Sheppard, E. L. Sproston, Noel D. McCarthy, Iain D Ogden, Ken J. Forbes, Marion MacRae, Norval J. C. Strachan, Martin C. J. Maiden, John F. Dallas, Fraser J. Gormley |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
DNA
Bacterial Disease reservoir Veterinary medicine Turkeys Genotype Swine Campylobacteriosis Food Contamination Campylobacter coli medicine.disease_cause Microbiology Campylobacter jejuni Article Poultry Species Specificity Campylobacter Infections medicine Environmental Microbiology Food microbiology Animals Humans Typing Disease Reservoirs biology Campylobacter General Medicine medicine.disease biology.organism_classification Bacterial Typing Techniques Scotland Food Microbiology Multilocus sequence typing Cattle Chickens Sequence Analysis Food Science |
| Popis: | A nationwide multi-locus sequence typing (MLST) survey was implemented to analyze patterns of host association among Campylobacter jejuni and Campylobacter coli isolates from clinical disease in Scotland (July 2005-September 2006), food animals (chickens, cattle, sheep, pigs and turkey), non-food animals (wild birds) and the environment. Sequence types (STs) were determined for 5247 clinical isolates and 999 from potential disease sources (augmented with 2420 published STs). Certain STs were over represented among particular sample sets/host groups. These host-associated STs were identified for all sample groups in both Campylobacter species and host associated clonal complexes (groups of related STs) were characterized for C. jejuni. Some genealogical lineages were present in both human disease and food animal samples. This provided evidence for the relative importance of different infection routes/food animal sources in human disease. These results show robust associations of particular genotypes with potential infection sources supporting the contention that contaminated poultry is a major source of human disease. |
| Databáze: | OpenAIRE |
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