Fever of unknown origin in Turkey: evaluation of 87 cases during a nine-year-period of study
| Autor: | Durdane Midikli, İsmail H. Dündar, Aslihan Sanli, Hasan Salih Zeki Aksu, Nese Saltoglu, Yeşim Taşova |
|---|---|
| Přispěvatelé: | Çukurova Üniversitesi |
| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Tuberculosis Adolescent Turkey Infections Fever of Unknown Origin Diagnosis Differential Internal medicine medicine Humans Fever of unknown origin Aged Aged 80 and over business.industry Brucellosis Fever of unknown origin (FUO) Middle Aged medicine.disease Surgery Adult Still's disease Infectious Diseases Atypical pneumonia Infective endocarditis Etiology Neoplasm Female business Vasculitis Encephalitis |
| Zdroj: | The Journal of infection. 48(1) |
| ISSN: | 0163-4453 |
| Popis: | PubMedID: 14667795 Objectives. To investigate fever of unknown origin (FUO) in 87 patients. Methods. We investigated 87 (61 male) patients with FUO using the criteria of Petersdorf and Beeson [Medicine 40 (1961 ) 1] hospitalized between January 1994 and August 2002 at Cukurova University Hospital. Results. The median age of the patients was 38.5 years (range: 14-80 years). Eleven patients (12.6%) were over 65. The mean duration of hospitalization was 22.5 ± 13 days. Infectious diseases were the most common causes of FUO. Tuberculosis (n = 15, 17.2%), infective endocarditis (n = 6), abdominal abscess (n = 6), brucellosis (n = 5), urinary tract infection (n = 5), visceral leishmaniasis (n = 4), salmonellosis (n = 3), rhinocerebral mucormycosis (n = 4), atypical pneumonia, cerebral toxoplasmosis, Cytomegalovirus infection or encephalitis were diagnosed in 51 (58.6%) patients. The second most common causes of FUO were collagen vascular diseases (n = 16, 18.3%) determined as vasculitis syndrome, adult Still's disease (n = 4), systemic lupus erythematosus, Behçet's disease, juvenile ankylosing spondylitis. Neoplasm was found in 12 (13.7%) patients; (non-Hodgkin lymphoma, Hodgkin lymphoma, chronic myeloid leukemia, gastrointestinal tract carcinoma, glioma). Miscellaneous diseases thyroiditis, granulomatous hepatitis were diagnosed in two (2.2%) patients. On admission, six patients (6.8%) were neutropenic. Conclusions. Infectious diseases, especially tuberculosis, were the leading diagnostic category of FUO in this study. Adult Still's disease was more common than expected. An aetiological diagnosis could not be reached in six (7%) patients who were followed for 1 year. Five of these patients completely recovered, and one patient died. © 2003 The British Infection Society. Published by Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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