Selective synthesis of 3-formylbenzofuran and 3-acylbenzofuran using a chalcone rearrangement strategy

Autor:	Akira Nakamura, Akira Imamiya, Yuichiro Ikegami, Fei Rao, Harumi Yuguchi, Yasuyoshi Miki, Tomohiro Maegawa
Rok vydání:	2022
Předmět:	General Chemical Engineering General Chemistry
Zdroj:	RSC advances. 12(47)
ISSN:	2046-2069
Popis:	We developed a method for highly selective synthesis of two benzofuran isomers, by rearranging and subsequently transforming 2-hydroxychalcones. Depending on the reaction conditions, synthesis of 3-formylbenzofurans, unconventional products, and 3-acylbenzofurans was achieved through cyclized 2,3-dihydrobenzofurans obtained from the rearranged products. The facile synthesis of 3-formylbenzofurans facilitated synthesis of the natural product, puerariafuran, from the corresponding chalcone.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e495bae2ec951a06554c2844f85359 https://pubmed.ncbi.nlm.nih.gov/36337936 Zobrazit plný text záznamu