Deficits in Emotion Recognition as Markers of Frontal Behavioral Dysfunction in Amyotrophic Lateral Sclerosis
| Autor: | Laura de Godoy Rousseff Prado, Patricia Lillo, Leonardo Cruz de Souza, Antônio Lúcio Teixeira, Eneida Mioshi, Aldrin Pedroza Martins |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Emotions Prefrontal Cortex Disease Behavioral Symptoms Motor symptoms 050105 experimental psychology 03 medical and health sciences Behavior disorder 0302 clinical medicine medicine Humans 0501 psychology and cognitive sciences Emotion recognition Cognitive decline Amyotrophic lateral sclerosis Aged business.industry 05 social sciences Amyotrophic Lateral Sclerosis Middle Aged medicine.disease Facial Expression Psychiatry and Mental health Social Perception Female Neurology (clinical) business Neuroscience Facial Recognition 030217 neurology & neurosurgery |
| Zdroj: | The Journal of neuropsychiatry and clinical neurosciences. 31(2) |
| ISSN: | 1545-7222 |
| Popis: | Objective: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with prominent motor symptoms. Patients with ALS may also manifest frontal behavior symptoms and cognitive decline, including impairment in facial emotion recognition. The authors aimed to investigate whether deficits in emotion recognition were associated with frontal behavior symptoms in ALS. Methods: Participants were patients with probable or definite sporadic ALS (N521; male:female ratio, 11:10; median age, 62 years; median disease duration, 3 years) and agematched and education-matched healthy control subjects (N525; male:female ratio, 14:11; median age, 61 years). The Facial Emotion Recognition Test (FERT) was administered to all participants. Patients with ALS were assessed using the Cambridge Behavior Inventory-Revised and were classified into two groups according to the presence of frontal behavioral symptoms: ALS with no behavioral symptom (ALSns; N59) and ALS with at least one behavioral symptom (ALSbs; N512). Results: Apathy and mood symptoms were the most frequent neuropsychiatric symptoms in the patient group. Patients with ALS performed worse than control subjects in the recognition of sadness (p,0.004). There were no differences between control subjects and patients in the ALSns group in all FERT scores, but the ALSbs group had lower performance than control subjects in sadness (p,0.003). Conclusions: Emotion recognition deficit may be a marker of frontal behavior in ALS. |
| Databáze: | OpenAIRE |
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