A Clinicopathologic Study of Six Cases of Lipoid Proteinosis
| Autor: | Gérald Pierard, Charles M. Lapière, Budo J, Van Cauwenberge D |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Basement membrane
Reticular fiber Pathology medicine.medical_specialty Staining and Labeling Chemistry Dermatology General Medicine Lipid Metabolism Lipidoses Basement Membrane Pathology and Forensic Medicine medicine.anatomical_structure Dermis medicine Humans Lipoid Proteinosis of Urbach and Wiethe Proteoglycans Facial Dermatoses |
| Zdroj: | The American Journal of Dermatopathology. 10:300-305 |
| ISSN: | 0193-1091 |
| DOI: | 10.1097/00000372-198808000-00004 |
| Popis: | We have reviewed the clinical and histological presentations of six cases of lipoid proteinosis. Deposits in the dermis were heterogeneous in nature and location. In the first stage of the disease's evolution, basement membrane components accumulate at the normal site of vascular, muscular, and epithelial basement membranes. Later on, lipids and amorphous material fill the superficial dermis, pushing apart the normal collagen bundles. Such deposits seem to be organized around preserved reticulin fibers. The amorphous material did not react with antibodies to collagen types I, III, IV, and V. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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