Tradeoffs in Cherenkov Detection for Positron Emission Tomography
| Autor: | Edoardo Charbon, Andrada Muntean, Esteban Venialgo, Claudio Bruschini, Francesco Gramuglia |
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| Rok vydání: | 2018 |
| Předmět: |
Physics
Scintillation Photon Physics::Instrumentation and Detectors 010308 nuclear & particles physics business.industry Astrophysics::High Energy Astrophysical Phenomena Detector Scintillator 01 natural sciences Coincidence Particle detector 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Optics 0103 physical sciences business Cherenkov radiation Jitter |
| Zdroj: | 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC). |
| Popis: | The coincidence time resolution (CTR) of a time-of-flight positron emission tomography (TOF-PET) scanner is an essential parameter, which determines signal-to-noise ratio (SNR) in image reconstruction algorithms. CTR has an important impact on scintillation-based detectors used in TOF-PET. Cherenkov PET has emerged as a prompt-photon based radiation detector, which has more accurate light-photon emission statistics. However, light transport becomes a dominant degradation effect in the light-photon detection statistics, which is highly correlated to the crystal length and consequently to the gamma-photon detection efficiency.This work focuses on finding the optimal design in terms of timing resolution and gamma-photon detection efficiency for Cherenkov detectors. Radiator design considerations such as size, materials and coatings, along with electronic jitter, and dark count rate (DCR), are included in a mathematical simulation that determines their effect on timing resolution. Currently, two different scintillators were simulated, namely PbF2 and PbWO4, with a maximum Cherenkov count per frame of 12 photons; an electronic jitter of 4.3ps to 42.5ps (standard deviation) was added. Simulation results confirm the high impact of jitter on the uncertainty of arrival times of Cherenkov photons. |
| Databáze: | OpenAIRE |
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