Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months’ follow-up
| Autor: | Deianira Luciani, Matteo Cadossi, Eugenio Chiarello, Sandro Giannini, Federico Tesei |
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| Přispěvatelé: | Luciani D, Cadossi M, Tesei F, Chiarello E, Giannini S |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Ankle osteoarthritis medicine.medical_specialty Painful ankle Pain Osteoarthritis Severity of Illness Index Viscosupplementation Adjuvants Immunologic Synovial Fluid ankle medicine Humans In patient Prospective Studies Hyaluronic Acid Range of Motion Articular Prospective cohort study Aged Viscosity business.industry General Medicine Middle Aged medicine.disease Surgery Radiography Treatment Outcome medicine.anatomical_structure Orthopedic surgery Female Ankle business Ankle Joint hyaluronan derivate Follow-Up Studies |
| Zdroj: | La Chirurgia degli Organi di Movimento. 92:155-160 |
| ISSN: | 1973-2538 0009-4749 |
| DOI: | 10.1007/s12306-008-0066-z |
| Popis: | BACKGROUND: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle. METHODS: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months. RESULTS: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p |
| Databáze: | OpenAIRE |
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