Making sense of post-treatment surveillance in head and neck cancer: when and what of follow-up

Autor: Raghav C. Dwivedi, Christopher M. Nutting, Rehan Kazi, Shailesh Khode, Kapila Manikantan, Rajan Palav, Peter Rhys-Evans, Kevin J. Harrington
Rok vydání: 2009
Předmět:
Zdroj: Cancer Treatment Reviews. 35:744-753
ISSN: 0305-7372
DOI: 10.1016/j.ctrv.2009.08.007
Popis: Follow-up in patients treated for head and neck cancer (HNC) is aimed at early detection of recurrence, metastases and second primary tumours. Various modalities for the routine follow-up of patients with HNC have been proposed and studied in the literature. Consequently, practising head and neck surgeons and oncologists all over the world use different guidelines and protocols to follow-up their patients. These guidelines involve follow-up intervals of varying intensity and schedule an assortment of investigations that may be neither logical nor practical. This follow-up process may be difficult to administrate, cause unnecessary discomfort and morbidity to the patient and can have serious cost-implications to the healthcare system. This review summarises strategies for follow-up, imaging modalities and key investigations in the literature published between 1980 and 2009. In this structured review, we have assessed studies in the literature that have addressed follow-up intervals, imaging tests, tumour markers, endoscopy and thyroid function tests as a part of the routine post-treatment surveillance in HNC patients. Studies analysing the cost benefit of such surveillance have also been addressed. Based on the evidence presented, we have compiled definitive recommendations for effective surveillance/post-treatment follow-up in patients with HNC.
Databáze: OpenAIRE