Cognitive impairment in schizoaffective disorder: a comparison with non-psychotic bipolar and healthy subjects

Autor:	Benedikt L. Amann, Manel Salamero, Eduard Vieta, Ana González-Pinto, Claire Daban, María Reinares, Rafael Tabarés-Seisdedos, Anabel Martínez-Arán, Antoni Benabarre, P. McKenna, Carla Torrent
Rok vydání:	2007
Předmět:	Adult Male Psychosis medicine.medical_specialty Bipolar Disorder Health Status Schizoaffective disorder Neuropsychological Tests Young Mania Rating Scale Severity of Illness Index Surveys and Questionnaires medicine Verbal fluency test Humans Bipolar disorder Psychiatry Demography Cognitive disorder Brain medicine.disease Psychiatry and Mental health Cross-Sectional Studies Psychotic Disorders Female Verbal memory Psychology Cognition Disorders Neurocognitive Clinical psychology
Zdroj:	Acta psychiatrica Scandinavica. 116(6)
ISSN:	1600-0447
Popis:	Objective: Only a few studies have examined specifically the neuropsychological performance of schizoaffective patients. Method: The sample consisted of 34 euthymic DSM-IV schizoaffective patients, who were compared with 41 euthymic bipolar patients without history of psychotic symptoms and 35 healthy controls. Euthymia was defined by a score of 6 or less at the Young Mania Rating Scale and a score of 8 or less at the Hamilton Depression Rating Scale for at least 6 months. Patients were compared with several clinical, occupational, and neuropsychological variables such as executive function, attention, verbal and visual memory and the two groups were contrasted with 35 healthy controls on cognitive performance. The three groups were compared using mancova after checking the potential role of several co-variables. Results: Schizoaffective patients showed greater impairment than controls and bipolar patients, in several domains, including verbal memory, executive function, and attentional measures. Bipolar patients without history of psychosis performed similar to the controls except for verbal fluency. Conclusion: Schizoaffective disorder carries more neurocognitive impairment than non-psychotic bipolar disorder and more occupational difficulties.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c4a6ac2e9b8bb82653a2fe6e4443c1 https://pubmed.ncbi.nlm.nih.gov/17997724 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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