Mediastinal Polyembryoma Associated With Klinefelter Syndrome
| Autor: | Wei Ming-Yu, Conrad V. Fernandez, Susan Sanderson, Elizabeth A. Cummings, Lisa Beresford, Michael Giacomantonio |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Pathology medicine.medical_specialty Isosexual precocious puberty Puberty Precocious Aneuploidy Mediastinal Neoplasms Paraneoplastic Endocrine Syndromes Gonadotropin-Releasing Hormone Klinefelter Syndrome Cell Movement Neoplastic Syndromes Hereditary Carcinoma Embryonal Adjuvant therapy Humans Medicine Chorionic Gonadotropin beta Subunit Human business.industry Mediastinum Thymus Neoplasms Hematology medicine.disease medicine.anatomical_structure Oncology Child Preschool Karyotyping Pediatrics Perinatology and Child Health Germinoma Germ cell tumors Teratoma Klinefelter syndrome business Polyembryoma |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 25:321-323 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/00043426-200304000-00011 |
| Popis: | A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he was found to have Klinefelter syndrome. Most mediastinal germ cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed. |
| Databáze: | OpenAIRE |
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