| Autor: |
Sergio Bea, Julio Hernández, Salvador F. Aliño, María José Herrero, Virginia Bosó, Luis Rojas, José Luis Poveda, Jaime Sánchez Plumed |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Current Issues and Future Direction in Kidney Transplantation |
| Popis: |
Optimizing balance between therapeutic efficacy and the occurrence of adverse events is the main goal of individualized medicine. This takes even more importance in narrow therapeutic index drugs such as immunosuppressants. These drugs are highly effective in preventing acute graft rejection but tacrolimus, cyclosporine and mycophenolic acid show highly variable pharmacokinetics and pharmacodynamics. Still nowadays the fragile equilibrium between the risks and benefits of immunosuppression makes the management of immunosuppressive pharmacotherapy a challenge. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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