Nanotherapeutics and Nanotheragnostics for Cancers: Properties, Pharmacokinetics, Biopharmaceutics, and Biosafety
| Autor: | Niels G A Willemen, Eliana B. Souto, Ana Sofia Ramos, Alexandra Abrantes, Margreet Morsink, Lucia Parente, Patrícia Severino, Inês Primo, Elena Sanchez-Lopez, Fernanda M. Silva |
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| Rok vydání: | 2022 |
| Předmět: |
Pharmacology
medicine.medical_specialty business.industry Biopharmaceutics Pharmaceutical market Containment of Biohazards Biosafety Drug Delivery Systems Nanomedicine Pharmacokinetics Neoplasms Drug Discovery medicine Cancer drug delivery Humans Nanoparticles Drug nanoparticles Intensive care medicine business Patient compliance |
| Zdroj: | Current Pharmaceutical Design. 28:104-115 |
| ISSN: | 1381-6128 |
| DOI: | 10.2174/1381612827666210804102645 |
| Popis: | With the increasing worldwide rate of chronic diseases, such as cancer, the development of novel techniques to improve the efficacy of therapeutic agents is highly demanded. Nanoparticles are especially well suited to encapsulate drugs and other therapeutic agents, bringing additional advantages, such as less frequent dosage requirements, reduced side effects due to specific targeting, and therefore increased patient compliance. However, with the increasing use of nanoparticles and their recent launch on the pharmaceutical market, it is important to achieve high-quality control of these advanced systems. In this review, we discuss the properties of different nanoparticles, the pharmacokinetics, the biosafety issues of concern, and conclude with novel nanotherapeutics and nanotheragnostics for cancer drug delivery. |
| Databáze: | OpenAIRE |
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