A Unique Case of Burkholderia cepacia Prosthetic Mitral Valve Endocarditis and Literature Review
Autor: | Tara H Lines, Jocelyn S. Gandelman, David M. Aronoff, Kelly Carpenter Byrge, Laura E. Dellalana, Anna K. Person |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty medicine.medical_treatment 030106 microbiology Ceftazidime Article 03 medical and health sciences 0302 clinical medicine Levofloxacin Mitral valve medicine Endocarditis 030212 general & internal medicine biology business.industry Mitral valve replacement biochemical phenomena metabolism and nutrition medicine.disease biology.organism_classification Surgery Infectious Diseases medicine.anatomical_structure Burkholderia Infective endocarditis bacteria Vancomycin business medicine.drug |
Zdroj: | Infect Dis Clin Pract (Baltim Md) |
ISSN: | 1536-9943 1056-9103 |
Popis: | Burkholderia cepacia prosthetic valve endocarditis (PVE) is extremely rare, with few cases in the literature. A report of a patient with PVE is described, followed by a literature review on B. cepacia PVE. A 38 year old man with poor dentition and a history of intravenous drug use (IVDU) and mitral valve replacement was found to have a mitral valve vegetation. Five sets of blood cultures on different days grew B. cepacia. Individual sets of blood cultures on different dates also isolated S. viridans (outside hospital culture), methicillin-resistant S. epidermidis (hospital day 1), and Bacillus spp. (hospital day 6). He was successfully treated with ceftazidime and levofloxacin as dual therapy for B. cepacia PVE, in addition to vancomycin for gram positive coverage. This case report and review highlights the possibility of B. cepacia PVE in immunocompetent patients with poor dentition, with the potential for a successful outcome following combination antimicrobial therapy. |
Databáze: | OpenAIRE |
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