Sclerosing angiomatoid nodular transformation (SANT) of spleen mimicking a splenic abscess: Case report and review of the literature
| Autor: | Carlo Cataldi, Pietro Fransvea, Saverio Cerasari, Francesca Stella, Sabrina Casale, Massimo Capaldi, Pierluigi Marini, Silvia Trombetta, Ricci G |
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| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.medical_treatment Splenectomy Spleen Article Lesion 03 medical and health sciences 0302 clinical medicine medicine Pathological health care economics and organizations business.industry SANT Splenic abscess Histology Abscess medicine.anatomical_structure 030220 oncology & carcinogenesis Etiology Immunohistochemistry 030211 gastroenterology & hepatology Surgery medicine.symptom business |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2019.02.015 |
| Popis: | Highlights • Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized benign, proliferative vascular lesion affecting the spleen. • A limited number of cases are described in the worldwide literature. • Further case studies are needed to elucidate the mechanism of SANT and its possible various etiologies. • In the light of above splenectomy at now is the choice treatment both for diagnosis and treatment. • This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Introduction SANT of the spleen is a benign lesion that does not recur after splenectomy with unknown etiology. Presentation of the case We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen mimicking a splenic abscess in a patient with imaging studies that failed to differentiate this lesion from other splenic lesions. Discussion SANT of the spleen is a rare condition, with only less than 100 cases reported in the literature. Clinically, SANT is only a kind of described pathological diagnostic conception. As in our case, these splenic lesions are often incidental findings on imaging studies performed for other reasons. Conclusion The patient was treated with splenectomy, which has proved to be both diagnostic and therapeutic. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis. |
| Databáze: | OpenAIRE |
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