SYMPATHICOTROPIC (LEYDIG) CELL TUMOR OF THE OVARY WITH VIRILISM: REPORT OF A CASE

Autor: E. H. Venning, Donald McEachern, Douglas Waugh
Rok vydání: 1949
Předmět:
Zdroj: The Journal of Clinical Endocrinology & Metabolism. 9:486-496
ISSN: 1945-7197
0021-972X
DOI: 10.1210/jcem-9-6-486
Popis: MASCULINIZATION due to ovarian tumor is rare, and it is only within the past few years that clinical and laboratory data concerning such cases have been gathered with sufficient completeness to establish some of the diagnostic criteria. Some examples of the condition must still go unrecognized, or pass as states of “functional” amenorrhea or mild hirsutism. In this paper we report a case, cured by surgical removal of the tumor, which presents features of diagnostic interest, clinically and pathologically. CASE HISTORY Mrs. D. M., age 46, was admitted to the Montreal Neurological Institute on September 25, 1946. She complained of amenorrhea of eleven years' duration; increased hair growth on the body for six years; loss of libido, nervousness, increased fatigability and a tendency to baldness of the scalp for five years; and huskiness of the voice for one and a half years. She had been in perfect health and had normal menstrual periods until eleven years before admission. At that time her periods suddenly ...
Databáze: OpenAIRE