ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

Autor: Juliane Strietz, Qingyan Au, Melanie Boerries, Mihee M. Kim, Jochen Maurer, Stella S. Stepputtis, Robert G. Oshima, David J. Castro, Peter Bronsert, Elmar Stickeler, Bernhard Kuster, Pedro Aza-Blanc, Thomas Brabletz, Bogdan-Tiberius Preca, Susanne Heynen-Genel, Corinne Vannier, Hauke Busch
Rok vydání: 2016
Předmět:
0301 basic medicine
Oncology
Pathology
Time Factors
Triple Negative Breast Neoplasms
Mice
SCID
Indole Alkaloids
Mice
Inbred NOD
Differentiation therapy
kinase knockdown
Caseins
Cell Differentiation
Tumor Burden
3. Good health
Gene Expression Regulation
Neoplastic
Phenotype
differentiation therapy
Neoplastic Stem Cells
ALPK1
Female
RNA Interference
Signal Transduction
Research Paper
medicine.medical_specialty
Carbazoles
Antineoplastic Agents
Protein Serine-Threonine Kinases
Transfection
Gene Expression Regulation
Enzymologic
03 medical and health sciences
Breast cancer
Cell Line
Tumor
Internal medicine
Endoribonucleases
human bi-potential tumor-initiating cells
medicine
Animals
Humans
ddc:610
Protein Kinase Inhibitors
Cell Proliferation
Dose-Response Relationship
Drug
business.industry
Myoepithelial cell
Cancer
ERN1
medicine.disease
Molecular medicine
Keratin 5
030104 developmental biology
Keratin 8
Keratin-5
business
Protein Kinases
Zdroj: OncoTarget 7(50), 83278-83293 (2016). doi:10.18632/oncotarget.13086
Oncotarget
ISSN: 1949-2553
DOI: 10.18632/oncotarget.13086
Popis: OncoTarget 7(50), 83278-83293 (2016). doi:10.18632/oncotarget.13086
Published by Impact Journals LLC, [S.l.]
Databáze: OpenAIRE
Externí odkaz: