Subclinical early posttraumatic seizures detected by continuous EEG monitoring in a consecutive pediatric cohort

Autor: Raman Sankar, Daniel H. Arndt, Joyce H. Matsumoto, Michelle Leung, Sue Yudovin, Andranik Madikians, Christopher C. Giza, Amy R. Brooks-Kayal, David L. McArthur, Conrad W. Szeliga, Hannah Valino, Farzad D. Buxey, Jason T. Lerner, Joyce Y. Wu, Michele Van Hirtum-Das
Rok vydání: 2013
Předmět:
Male
Epilepsies
Neurodegenerative
Epilepsy
Status Epilepticus
Risk Factors
Prospective Studies
Prospective cohort study
Child
Children
Subclinical infection
Pediatric intensive care unit
Pediatric
Head injury
Electroencephalography
Injuries and accidents
Neurology
Clinical neurophysiology
Child
Preschool
Anticonvulsants
Female
medicine.symptom
Partial
medicine.medical_specialty
Physical Injury - Accidents and Adverse Effects
Monitoring
Adolescent
Traumatic brain injury
Clinical Sciences
Status epilepticus
Traumatic Brain Injury (TBI)
Article
Clinical Research
Seizures
Internal medicine
medicine
Humans
Glasgow Coma Scale
Physiologic
Preschool
Traumatic Head and Spine Injury
Monitoring
Physiologic
Neurology & Neurosurgery
business.industry
Neurosciences
Infant
medicine.disease
Surgery
Brain Disorders
Brain Injuries
ICU
Neurology (clinical)
Epilepsies
Partial
business
Zdroj: Epilepsia, vol 54, iss 10
ISSN: 1528-1167
Popis: Summary Purpose Traumatic brain injury (TBI) is an important cause of morbidity and mortality in children, and early posttraumatic seizures (EPTS) are a contributing factor to ongoing acute damage. Continuous video-EEG monitoring (cEEG) was utilized to assess the burden of clinical and electrographic EPTS. Methods Eighty-seven consecutive, unselected (mild – severe), acute TBI patients requiring pediatric intensive care unit (PICU) admission at two academic centers were monitored prospectively with cEEG per established clinical TBI protocols. Clinical and subclinical seizures and status epilepticus (SE, clinical and subclinical) were assessed for their relation to clinical risk factors and short-term outcome measures. Key Findings Of all patients, 42.5% (37/87) had seizures. Younger age (p = 0.002) and injury mechanism (abusive head trauma – AHT, p
Databáze: OpenAIRE
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