Urea for hyponatremia?
| Autor: | John K. Hix, Richard H. Sterns, Stephen M. Silver |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty business.industry medicine.drug_class medicine.medical_treatment nutritional and metabolic diseases medicine.disease Cerebral edema Clinical trial Transplantation chemistry.chemical_compound chemistry Nephrology medicine Urea Animals Intensive care medicine business Hyponatremia Vasopressin Antagonists Dialysis Antidiuretic |
| Zdroj: | Kidney International. 87:268-270 |
| ISSN: | 0085-2538 |
| DOI: | 10.1038/ki.2014.320 |
| Popis: | Once the standard of care for cerebral edema, urea can also be used to treat hyponatremia. The 2014 European Clinical Practice Guidelines recommend urea for the treatment of the syndrome of inappropriate antidiuretic hormone, while discouraging use of vasopressin antagonists. Although there is evidence that urea can diminish hypertonic injury to brain cells caused by rapid correction of hyponatremia, clinical trials are needed that include patients at high risk to develop complications from overcorrection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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