An autopsy case of idiopathic pulmonary fibrosis with remarkable honeycomb cyst expansion

Autor: Yu Ito, Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Mari Tone, Kohei Takada, Kazushi Fujimoto, Yutaka Muto, Toshio Kumasaka, Takehiro Izumo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 36, Iss, Pp 101588-(2022)
Respiratory Medicine Case Reports
ISSN: 2213-0071
Popis: Herein, we report an autopsy case of idiopathic pulmonary fibrosis (IPF) in which remarkable honeycomb cyst expansion appeared in the clinical course. Radiological findings initially showed subpleural predominant reticulation that had progressed to usual interstitial pneumonia with honeycomb cysts, along with a restrictive pattern in the pulmonary function tests. The diameter of honeycomb cysts had gradually increased, and some cysts had abruptly expanded at the end stage. Based on pathological findings of autopsy specimens, bronchiectasis, alveolar collapse due to inflammation, and check-valve mechanism caused by a slit-like orifice of the cysts could have contributed to honeycomb cyst expansion.
Databáze: OpenAIRE