Variability of electrochemical skin conductance for screening diabetes mellitus
| Autor: | Ho-ryong Yoo, Min-Ho Jun, Gahye Kim, Jaeuk U. Kim, Soochan Kim, Sangsoo Park, Boncho Ku, JungHee Cho |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
0206 medical engineering Biomedical Engineering 02 engineering and technology Type 2 diabetes 01 natural sciences Gastroenterology 010309 optics Internal medicine Diabetes mellitus 0103 physical sciences medicine reproductive and urinary physiology Meal urogenital system business.industry Screening diabetes Area under the curve Control subjects medicine.disease 020601 biomedical engineering embryonic structures Original Article biological phenomena cell phenomena and immunity business Skin conductance Body mass index |
| Zdroj: | Biomedical Engineering Letters. 9:267-274 |
| ISSN: | 2093-985X 2093-9868 |
| Popis: | Electrochemical skin conductance (ESC) has been suggested as a noninvasive diabetic screening tool. We examined the relevance of ESC method for screening type 2 diabetes. A meal tolerance test (MTT) was conducted for 40 diabetic and 42 control subjects stratified by age, sex and body mass index (BMI). The glucose levels and ESC were measured before the MTT and every 30 min after meal intake up to 120 min. There was no correlation between the blood glucose level and ESC (r = 0.249) or ESC variability (ESCV) (r = − 0.173). ESC (ESCV) was higher (lower) in diabetic patients than in normal control (p = 0.02 for ESC and p = 0.06 for ESCV). Receiver operating characteristic analysis showed that the area under the curve (AUC) values of the ESC and ESCV were 0.654 and 0.691, respectively. The novel variable, ESCV, showed 5.7% higher AUC than ESC. Contrary to some previous reports, ESC values in diabetic patients was higher than in age, sex and BMI matched control group. In our study, ESC or ESCV showed a marginal accuracy to be used as a screening tool for diabetes mellitus. |
| Databáze: | OpenAIRE |
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