Secreting vagal paraganglioma
| Autor: | Jan C. Groblewski, Apurva A. Thekdi, Ricardo L. Carrau |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
medicine.medical_specialty Urinary system Neck mass Asymptomatic Paraganglioma medicine Humans Head and neck Vagal paraganglioma business.industry Vagus Nerve Middle Aged medicine.disease Hypertensive crisis Magnetic Resonance Imaging Vagus nerve Surgery Otorhinolaryngology Head and Neck Neoplasms Female Radiology medicine.symptom business Tomography X-Ray Computed Neck |
| Zdroj: | American journal of otolaryngology. 25(4) |
| ISSN: | 0196-0709 |
| Popis: | Paragangliomas are rare tumors that derive from neural crest tissue. Vagal paragangliomas account for only 3% of all head and neck paragangliomas. Patients with vagal paragangliomas typically present with an asymptomatic neck mass and, less frequently, with cranial neuropathies. It is estimated that only 1% to 3% of all head and neck paragangliomas secrete catecholamines. The incidence of secreting vagal paragangliomas is even smaller. The diagnosis of a secreting paraganglioma involves the use of a screening test for serum catecholamines and a 24-hour urinary test for catecholamine metabolites. The identification and staging of these tumors can be performed through the use of MRI and/or CT scans and an octreotide scintigraphy. The mainstay treatment is surgical extirpation; however, preoperative medical blockade is critical to avoid a hypertensive crisis intra-operatively. We present two illustrative cases of secreting vagal paragangliomas involving a complex diagnostic and therapeutic algorithm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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