The rate of SARS-CoV-2 positivity in asymptomatic pregnant women admitted to hospital for delivery: Experience of a pandemic center in Turkey

Autor: Dilek Sahin, Aziz Ahmet Surel, Elif Gül Yapar Eyi, Bedia Dinc, Hüseyin Levent Keskin, Seyit Ahmet Erol, Gülin Feykan Yeğin, Elçin İşlek Seçen, Fisun Kirca, Ozlem Moraloglu Tekin, Serpil Unlu, Atakan Tanacan, Şebnem Özyer, Ali Taner Anuk, Batuhan Turgay
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
medicine.medical_specialty
COVID-19 Vaccines
Turkey
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Pneumonia
Viral
Prenatal diagnosis
Asymptomatic
Article
Betacoronavirus
03 medical and health sciences
COVID-19 Testing
0302 clinical medicine
Risk Factors
Pregnancy
Prenatal Diagnosis
Pandemic
Obstetrics and Gynaecology
Humans
Medicine
Prospective Studies
030212 general & internal medicine
Pregnancy Complications
Infectious
Risk factor
Prospective cohort study
Asymptomatic Infections
Pandemics
030219 obstetrics & reproductive medicine
Clinical Laboratory Techniques
SARS-CoV-2
business.industry
Obstetrics
COVID-19
Obstetrics and Gynecology
medicine.disease
Hospitalization
Asymptomatic patients
Reproductive Medicine
Female
medicine.symptom
Coronavirus Infections
business
Zdroj: European Journal of Obstetrics & Gynecology and Reproductive Biology
European Journal of Obstetrics, Gynecology, and Reproductive Biology
ISSN: 0301-2115
DOI: 10.1016/j.ejogrb.2020.07.051
Popis: Objective To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in asymptomatic pregnant women admitted to hospital for delivery in a Turkish pandemic center. Study Design This prospective cohort study was conducted in Ankara City Hospital between April, 15, 2020 and June, 5, 2020. A total of 206 asymptomatic pregnant women (103 low-risk pregnant women without any defined risk factor and 103 high-risk pregnant women) were screened for SARS-CoV-2 positivity upon admission to hospital for delivery. Detection of SARS-CoV2 in nasopharyngeal and oropharyngeal samples was performed by Real Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) method targeting RdRp (RNA dependent RNA polymerase) gene. Two groups were compared in terms of demographic features, clinical characteristics and SARS-CoV-2 positivity. Results Three of the 206 pregnant women participating in the study had positive RT-PCR tests (1.4 %) and all positive cases were in the high-risk pregnancy group. Although, one case in the high-risk pregnancy group had developed symptoms highly suspicious for COVID-19, two repeated RT-PCR tests were negative. SARS-CoV-2 RT-PCR positivity rate was significantly higher in the high-risk pregnancy group (2.9 % vs 0%, p = 0.04). Conclusion Healthcare professionals should be cautious in the labor and delivery of high-risk pregnant women during the pandemic period and universal testing for COVID-19 may be considered in selected populations.
Databáze: OpenAIRE
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